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CentrivaLab™

High-Throughput Centrifugal Membrane Screening

CentrivaLab is a rotor-matched cartridge platform for rapid screening of nanofiltration (NF) and reverse osmosis (RO) membranes under controlled hydrodynamic conditions, based on Ortho-Centrifugal Membrane Filter (O-CMF) technology. Validated against bench-scale crossflow units, it delivers uniform pressure, minimal polarization, and scalable results.

Explore Configurations Scientific Validation

Current Standard Configuration

CentrivaLab 50/34°
Designed for 50 mL fixed-angle rotors at 34°. Supports up to 50 bar pressure for NF/RO.

Custom versions available for other 50 mL or 96–100 mL formats.

Technology

CentrivaLab leverages the Ortho-Centrifugal Membrane Filter (O-CMF) principle, where centrifugal force drives permeation through a flat-sheet membrane positioned for uniform pressure and reproducible hydrodynamics. Introduced in seminal research and validated for scaled-down screening, O-CMF ensures minimal concentration polarization via centrifugal convection, as confirmed by CFD simulations.

Graphical abstract of Ortho-Centrifugal Membrane Filter (O-CMF) technology
O-CMF device schematic showing uniform pressure design

Available Configurations

CentrivaLab cartridges are rotor-specific and customizable to match tube volume, rotor angle, and centrifuge geometry.

CentrivaLab 50/34°

Current Standard Configuration
  • Designed for 50 mL fixed-angle rotors at 34°
  • Sample volume: up to 15 mL
  • Suitable for NF/RO membrane screening
  • Optimized for controlled concentration polarization
  • Ready for immediate rollout

Custom Rotor-Matched Designs

Manufactured on Request
  • Other 50 mL rotor geometries
  • 96–100 mL rotor formats
  • Rotor angle-specific matching
  • Geometry tailored to centrifuge envelope
  • Material and chamber-volume customization

Materials

Available Materials

  • Acrylic resin (for rapid prototyping)
  • PES (polyethersulfone, for aqueous screening)
  • PEEK (for chemically demanding systems/OSN)

Typical Use Cases

  • Rapid prototyping and early testing
  • Aqueous membrane screening
  • Chemically demanding systems
  • OSN-oriented development pathways

Why CentrivaLab?

Validated against bench-scale crossflow units, CentrivaLab combines low sample consumption (<10 mL), rapid turnaround (~5 min assembly), near-zero permeate hold-up, and realistic (spiral-wound-like) concentration polarization for efficient membrane screening.

Feature CentrivaLab / O-CMF Crossflow Test Cells Pressurized Stirred Cells
Minimum Feed Volume <10 mL ~1 L ~30 mL
Assembly Time (6 cells) ~5 min ~30 min ~30 min
Feed Replacement (6 cells) ~5 min ~15 min ~15 min
Permeate Retention Virtually zero ~1 mL / cell ~1 mL / cell
Concentration Polarization Uniform and spiral-wound-like Realistic Non-uniform
Pump Required No Yes Typically yes
Throughput Hundreds of tests per day per centrifuge Low Low to moderate

Scientific Validation

CentrivaLab is grounded in peer-reviewed research on O-CMF design, hydrodynamics, concentration polarization, and scaled-down membrane screening. An upcoming article co-authored with Professor Menachem Elimelech will further advance predictive modeling.

Seminal Paper
Designing Centrifugal Membrane Filters with Uniform-Pressure for UF/NF/RO Separations
Journal of Membrane Science (2024)
Introduced the O-CMF concept, demonstrating uniform transmembrane pressure, reduced concentration polarization, CFD-supported analysis, and suitability for membrane characterization, screening, and purification.
Scaled-Down Membrane Screening Validation
Ortho-Centrifugal Membrane Filter for Scaled-Down High-Throughput Screening of Nanofiltration Membranes
Separation and Purification Technology (2025)
Validated O-CMF against a standard crossflow bench-scale unit, showing comparable hydraulic permeabilities, fluxes, rejections, and concentration polarization behavior.
Doctoral Application Work
From Pulp to Prebiotics: Xylooligosaccharides Production from Eucalyptus Bleached Kraft Pulp and Enhanced Purification Using a Novel High-Throughput Membrane Screening Technique
Patrícia Isabel Antunes Henriques (2024)
Demonstrates application of the screening concept in a broader process and purification context.
Ongoing Predictive Modeling Framework
Predictive Modeling of Multicomponent Concentration Polarization in Ortho-Centrifugal NF/RO Membrane Screening
Manuscript in Preparation (co-authored with Prof. Menachem Elimelech)
Extends the physical framework toward predictive concentration polarization modeling and intrinsic scaling for NF/RO screening.

Research Cartridges Available on Request

CentrivaLab cartridges are manufactured on demand through Talentground Lda. Current focus is on scientific and technical collaboration, custom rotor matching, and research use in membrane screening and characterization workflows.

FAQ: How do I order?

Use the form above for custom quotes. Pricing starts at €X for standard kits (contact for details).

FAQ: Is it compatible with my centrifuge?

We match designs to your rotor specs—send details for a free assessment.